Integrative Kidney Physiology and Pathophysiology IKPP

Research

The declared aim of IKPP is to offer excellent training and research opportunities to young researchers in the fields of renal physiology and pathophysiology.

Chronic Kidney Disease (CKD): the silent epidemic. CKD is a progressive condition due to irreversible kidney damage and loss of function. Recent data show that I0% of the world population has some degree of CKD, sometimes progressing to dialysis or transplantation. The CKD prevalence is rising because it is linked to other modern epidemics such as obesity, hypertension or diabetes. Worldwide more than 50 million people are affected, leading to costs of more than 6% of health care budgets. Unfortunately, in most cases people are unaware of the fact that they have CKD. In a recent meeting at the European Parliament, the European Kidney Health Alliance called for European health policies to support early identification and treatment of CKD. Efforts should be pulled together at European level by putting the prevention of CKD high on the agenda, through exchange of best practices between Member States and improvement of existing technologies for early CKD detection. The main reason for the devastating consequences of impaired renal function is the central role of the kidneys in body homeostasis. 

The IKPP network of nephrologists and renal physiologists builds on a longstanding and strong tradition in Switzerland. With the EU (European Commission) funded programmes IKPP1 and IKPP2, which have been established at the University of Bern, we have been providing a field for young postdoctoral fellows to deepen their understanding of the kidneys’ function for body homeostasis. IKPP1 and IKPP2 have been set up at Swiss universities in very close collaboration with the Swiss National Centre of Competence in Research Kidney Control of Homeostasis NCCR Kidney.CH.  IKPP offers fellowships for international postdoctoral fellows and aims at strengthening integrative thinking and awareness for kidney-centered homeostatic systems. The IKPP and NCCR Kidney.CH programme have been successful at training a new generation of talented kidney researchers since 2010, and have thus substantially helped to improve the research quality of the European Research Area. IKPP has cooperations with a large range of departments of the Swiss universities, such as the Divisions of Nephrology, Hypertension and Clinical Pharmacology and Visceral Surgery of the University of Bern, the Institute of Physiology and the Institute of Anatomy of the University of Zurich, the Department of Pharmaceutical Sciences of the University of Basel, the Department of Pharmacology and Toxicology of the University of Lausanne, or the Departments of Internal Medicine Specialities and Cell Physiology and Metabolism of the University of Geneva, as well as all the other institutional members of the NCCR Kidney.CH.